Publications

Schneeberger K., Voigt CC.
Virus ecology and conservation of bats.
In: Bats in the Anthropocene: Conservation of bats in a changing world (eds. Voigt CC, Kingston T.)
Springer e-book. accepted

Fischer K, Zeus V, Kwasnitschka L, Kerth G, Haase M, Groschup MH, Balkema-Buschmann A (2015).
Insectivorous bats carry host specific astroviruses and coronaviruses across different regions in Germany.
Infection, Genetics and Evolution, accepted for publication

Donata Hoffmann, Annika Franke, Maria Jenckel, Aistė Tamošiūnaitė, Julia Schluckebier, Harald Granzow, Bernd Hoffmann, Stefan Fischer, Rainer G. Ulrich, Katja Goller, Nikolaus Osterrieder, Martin Beer.
Out of the reservoir: Phenotypic 1 and genotypic characterization of a novel cowpox virus isolated from a common vole.
J. Virol. 2015, accepted

Gryseels S, Rieger T, Oestereich L, Cuypers B, Borremans B, Makundi R, Leirs H, Günther S, Goüy de Bellocq J.
Gairo virus, a novel arenavirus of the widespread Mastomys natalensis: Genetically divergent, but ecologically similar to Lassa and Morogoro viruses.
Virology. 2015 476:249-56.

Gryseels S, Leirs H, Makundi R, Goüy de Bellocq J.
Polymorphism in vkorc1 Gene of Natal Multimammate Mice, Mastomys natalensis, in Tanzania.
J Hered. 2015.

Schuberth-Wagner C, Ludwig J, Bruder AK, Herzner AM, Zillinger T, Goldeck M, Schmidt T, Schmid-Burgk JL, Kerber R, Wolter S, Stümpel JP, Roth A, Bartok E, Drosten C, Coch C, Hornung V, Barchet W, Kümmerer BM, Hartmann G, Schlee M.
A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2′O-Methylated Self RNA.
Immunity. 2015 Jul 21;43(1):41-51.

Weber F.
The catcher in the RIG-I.
Cytokine. 2015 Jul 10. pii:S1043-4666(15)30012-0.

Muth D, Corman VM, Meyer B, Assiri A, Al-Masri M, Farah M, Steinhagen K, Lattwein E, Al-Tawfiq JA, Albarrak A, Müller MA, Drosten C, Memish ZA.
Infectious MERS-Coronavirus excretion and serotype variability based on live virus isolates from patients in Saudi Arabia.
J Clin Microbiol. 2015 Jul 8. pii: JCM.01368-15.

Weber de Melo V, Sheikh Ali H, Freise J, Kühnert D, Essbauer S, Mertens M, Wanka KM, Drewes S, Ulrich RG, Heckel G.
Spatiotemporal dynamics of Puumala hantavirus associated with its rodent host, Myodes glareolus.
Evol Appl. 2015 Jul;8(6):545-59.

Marklewitz M, Zirkel F, Kurth A, Drosten C, Junglen S.
Evolutionary and phenotypic analysis of live virus isolates suggests arthropod origin of a pathogenic RNA virus family.
Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):7536-41.

Voßmann S, Wieseler J, Kerber R, Kümmerer BM.
A basic cluster in the N terminus of yellow fever virus NS2A contributes to infectious particle production.
J Virol. 2015 May;89(9):4951-65.

Borremans B, Vossen R, Becker-Ziaja B, Gryseels S, Hughes N, Van Gestel M, Van, Houtte N, Günther S, Leirs H.
Shedding dynamics of Morogoro virus, an African arenavirus closely related to Lassa virus, in its natural reservoir host Mastomys natalensis.
Sci Rep. 2015 May 29;5:10445

Müller MA, Meyer B, Corman VM, Al-Masri M, Turkestani A, Ritz D, Sieberg A, Aldabbagh S, Bosch BJ, Lattwein E, Alhakeem RF, Assiri AM, Albarrak AM, Al-Shangiti AM, Al-Tawfiq JA, Wikramaratna P, Alrabeeah AA, Drosten C, Memish ZA.
Presence of Middle East respiratory syndrome coronavirus antibodies in Saudi Arabia: a nationwide, cross-sectional, serological study.
Lancet Infect Dis. 2015 May;15(5):559-64.

Weber M, Sediri H, Felgenhauer U, Binzen I, Bänfer S, Jacob R, Brunotte L, Garcia-Sastre A, Schmid-Burgk J, Schmidt T, Hornung V, Kochs G, Schwemmle M, Klenk HD. Weber F.
Influenza virus adaptation PB2-627K modulates nucleocapsid inhibition by the pathogen sensor RIG-I.
Cell Host Microbe. 2015 Mar 11;17(3):309-19.

Tkachenko EA, Witkowski PT, Radosa L, Dzagurova TK, Okulova NM, Yunicheva YV, Vasilenko L, Morozov VG, Malkin GA, Krüger DH, Klempa B.
Adler hantavirus, a new genetic variant of Tula virus identified in Major’s pine voles (Microtus majori) sampled in southern European Russia.

Infect Genet Evol. 2015 Jan;29:156-63.

Zhiyong Xu, Dimitrios Zikos, Aiste˙ Tamošiunaite˙, Robert Klopfleisch, Nikolaus Osterrieder, Karsten Tischer.
Identification of 10 Cowpox Virus Proteins That Are Necessary for Induction of Hemorrhagic Lesions (Red Pocks) on Chorioallantoic Membranes.
J. Virol., 2014. vol. 88 no. 15 pp. 8615-8628

Borremans B, Hughes NK, Reijniers J, Sluydts V, Katakweba AAS, Mulungu LS, Sabuni CA, Makundi RH, Leirs H.
Happily together forever: temporal variation in spatial patterns and complete lack of territoriality in a promiscuous rodent.
Popul Ecol. 2014 56(1):109-18

Kallies R, Kopp A, Zirkel F, Estrada A, Gillespie TR, Drosten C, Junglen S.
Genetic characterization of goutanap virus, a novel virus related to negeviruses, cileviruses and higreviruses.
Viruses. 2014 Nov 12;6(11):4346-57.

Corman VM, Ithete NL, Richards LR, Schoeman MC, Preiser W, Drosten C, Drexler JF.
Rooting the phylogenetic tree of MERS-Coronavirus by characterization of a conspecific virus from an African Bat.
J Virol. 2014 Oct;88(19):11297-303.

Schuster S, Zirkel F, Kurth A, van Cleef KW, Drosten C, van Rij RP, Junglen S.
A unique Nodavirus with novel features: Mosinovirus expresses two subgenomic RNAs, a capsid gene of unknown origin, and a suppressor of the antiviral RNAi pathway.
J Virol. 2014 Sep 10. pii: JVI.02144-14.

Drosten C, Meyer B, Müller MA, Corman VM, Al-Masri M, Hossain R, Madani H, Sieberg A, Bosch BJ, Lattwein E, Alhakeem RF, Assiri AM, Hajomar W, Albarrak AM, Al-Tawfiq JA, Zumla AI, Memish ZA.
Transmission of MERS-coronavirus in household contacts.
N Engl J Med. 2014 Aug 28;371(9):828-35.

van Cleef KW, van Mierlo JT, Miesen P, Overheul GJ, Fros JJ, Schuster S, Marklewitz M, Pijlman GP, Junglen S, van Rij RP.
Mosquito and Drosophila entomobirnaviruses suppress dsRNA- and siRNA-induced RNAi.
Nucleic Acids Res. 2014 Jul;42(13):8732-44.

Weber M, Weber F.
Monitoring activation of the antiviral pattern recognition receptors RIG-I and PKR by limited protease digestion and native PAGE.
J Vis Exp. 2014 Jul 29;(89):e51415.

Marz M, Beerenwinkel N, Drosten C, Fricke M, Frishman D, Hofacker IL, Hoffmann D, Middendorf M, Rattei T, Stadler PF, Töpfer A.
Challenges in RNA virus bioinformatics.
Bioinformatics. 2014 Jul 1;30(13):1793-9.

Lundin A, Dijkman R, Bergström T, Kann N, Adamiak B, Hannoun C, Kindler E, Jónsdóttir HR, Muth D, Kint J, Forlenza M, Müller MA, Drosten C, Thiel V, Trybala E.
Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virus.
PLoS Pathog. 2014 May 29;10(5):e1004166.

Borremans B.
Ammonium improves elution of fixed dried blood spots without affecting immunofluorescence assay quality.
Trop Med Int Health. 2014 Apr;19(4):413-6.

Rieger T, Merkler D, Günther S.
Infection of type I interferon receptor-deficient mice with various old world arenaviruses: a model for studying virulence and host species barriers.
PLoS One. 2013 8(8):e72290.

Goyens J, Reijniers J, Borremans B, Leirs H.
Density thresholds for Mopeia virus invasion and persistence in its host Mastomys natalensis.
J Theor Biol. 2013 317:55-61.

Colangelo P, Verheyen E, Leirs H, Tatard C, Denys C, Dobigny G, Duplantier JM, Brouat C, Granjon C, Lecompte E.
A mitochondrial phylogeographic scenario for the most widespread African rodent species, Mastomys natalensis.
Biological Journal of the Linnean Society. 2013 108(4):901-916.

Niemeyer D1, Zillinger T, Muth D, Zielecki F, Horvath G, Suliman T, Barchet W, Weber F, Drosten C, Müller MA.
Middle East respiratory syndrome coronavirus accessory protein 4a is a type I interferon antagonist.
J Virol. 2013 Nov;87(22):12489-95. doi: 10.1128/JVI.01845-13

Radosa L, Schlegel M, Gebauer P, Ansorge H, Heroldová M, Jánová E, Stanko M, Mošanský L, Fričová J, Pejčoch M, Suchomel J, Purchart L, Groschup MH, Krüger DH, Ulrich RG, Klempa B.
Detection of shrew-borne hantavirus in Eurasian pygmy shrew (Sorex minutus) in Central Europe.
Infect Genet Evol. 2013 Oct;19:403-10.

Reusken CB, Haagmans BL, Müller MA, Gutierrez C, Godeke GJ, Meyer B, Muth D, Raj VS, Vries LS, Corman VM, Drexler JF, Smits SL, El Tahir YE, De Sousa R, van Beek J, Nowotny N, van Maanen K, Hidalgo-Hermoso E, Bosch BJ, Rottier P, Osterhaus A, Gortázar-Schmidt C, Drosten C, Koopmans MP.
Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study.
Lancet Infect Dis. 2013 Oct;13(10):859-66.

Drexler JF, Geipel A, König A, Corman VM, van Riel D, Leijten LM, Bremer CM, Rasche A, Cottontail VM, Maganga GD, Schlegel M, Müller MA, Adam A, Klose SM, Borges Carneiro AJ, Stöcker A, Franke CR, Gloza-Rausch F, Geyer J, Annan A, Adu-Sarkodie Y, Oppong S, Binger T, Vallo P, Tschapka M, Ulrich RG, Gerlich WH, Leroy E, Kuiken T, Glebe D, Drosten C.
Bats carry pathogenic hepadnaviruses antigenically related to hepatitis B virus and capable of infecting human hepatocytes.
Proc Natl Acad Sci U S A. 2013 Sep 16.

Junglen S, Drosten C.
Virus discovery and recent insights into virus diversity in arthropods.
Curr Opin Microbiol. 2013 Aug;16(4):507-13.

Raj VS, Mou H, Smits SL, Dekkers DH, Müller MA, Dijkman R, Muth D, Demmers JA, Zaki A, Fouchier RA, Thiel V, Drosten C, Rottier PJ, Osterhaus AD, Bosch BJ, Haagmans BL.
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC.
Nature. 2013 Mar 14;495(7440):251-4.

Kindler E, Jónsdóttir HR, Muth D, Hamming OJ, Hartmann R, Rodriguez R, Geffers R, Fouchier RA, Drosten C, Müller MA, Dijkman R, Thiel V.
Efficient replication of the novel human betacoronavirus EMC on primary human epithelium highlights its zoonotic potential.
MBio. 2013 Feb 19;4(1). pii: e00611-12.